Elravie Re2O is derived from human acellular dermal matrix (hADM) and processed with advanced extraction technology. It is KFDA approval and became a popular trend in South Korea since 2025. It delivers authentic ECM building blocks directly to the dermis:
- Collagen: 89%
- Elastin: 3%
- Hyaluronic Acid (GAGs): 0.4%
- Other ECM components: 7.6%
Rather than simply adding volume, Elravie Re2O restores the skin’s structural foundation—improving firmness, elasticity, and resilience from within.
Human acellular dermal matrix (hADM)–derived ECM supports anti-aging by restoring the skin’s structural microenvironment, not just surface volume or hydration. It works at the dermal level to improve skin quality from the source.
1. Rebuilds the Dermal Scaffold
The ECM forms the skin’s 3D framework—collagen, elastin, GAGs/HA, and structural proteins. As this network degrades with age, skin becomes lax, thin, and rough. hADM-derived ECM replenishes these core components, helping restore firmness and resilience.
2. Reactivates Fibroblasts
Fibroblasts slow down when ECM support declines. hADM-ECM delivers native human signals that improve cell adhesion and communication, encouraging renewed collagen and elastin production—resulting in natural, progressive rejuvenation.
3. Improves Density, Not “Filling”
Rather than pushing tissue apart like fillers, ECM integrates into the dermis, enhancing tissue density and quality from within. Skin looks smoother, firmer, and more refined—without stiffness or an overfilled appearance.
4. Enhances Overall Skin Quality
By supporting the entire dermal ecosystem, ECM improves firmness, elasticity, hydration, texture, pores, and barrier stability—earning its role as a true “skin quality booster.”
5. High Biocompatibility for Natural Results
Human-derived and acellular, hADM offers excellent tissue integration with minimal immune response, making it ideal for sensitive skin and long-term, natural-looking rejuvenation.
Elravie Re2O – Treatment Protocol
Preparation: Cleanse the skin thoroughly and apply topical anesthetic for 30–45 minutes. Reconstitute the 150 mg powder with 5 cc of saline and administer via skin booster (mesotherapy) injections for optimal results. For enhanced firming and hydration, the powder may alternatively be mixed with 5 cc saline and 2 cc non-crosslinked hyaluronic acid.
Solution: Reconstitute 150 mg Re2O powder with 5 cc saline + 2 cc non-crosslinked hyaluronic acid.
Injection Technique: Administer via multiple microinjections into the mid-dermal layer at 1.5–3 mm depth, adjusted for skin thickness.
Instruments: Use a 30G, 4 mm needle for uniform distribution. Injection devices may be used if necessary but are not recommended.
Treatment Area: Full face, targeting sagging, fine lines, enlarged pores, and overall skin texture.
Duration: 10–30 minutes per session; minimal discomfort expected.
- One session every 4 weeks.
- 3 to 5 sessions each treatment.
- Maintenance every 3–6 months after initial sessions
Elravie Re2O – Post-Treatment Care Protocol
Immediate Aftercare:
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Expect mild redness, swelling, bruising, or small bumps at injection sites (resolve in 1–3 days).
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Apply Luxevo Exobrant NMN bio-cellulose mask immediately post-treatment.
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Perform 25 minutes of LED light therapy.
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Optional: Use LDM RF device with aloe gel massage to enhance comfort.
Skin Care:
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Apply Luxevo Exobrant Balm regularly for 7 days.
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Use daily sunscreen and avoid direct sun exposure.
Restrictions (1 week):
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Avoid saunas, hot baths, heavy exercise, alcohol, and prolonged sun exposure.
Recovery:
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Face washing and makeup application are generally permitted the day after treatment.
Recommended Protocol
- One session every 4 weeks.
- 3 to 5 sessions each treatment.
- Maintenance every 3–6 months after initial sessions















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